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However, emerging evidence suggests a potential link between GLP-1 therapy and altered pain perception, possibly through several mechanisms: 1- Neuroinflammation and Microglial Activation: GLP-1 receptors are expressed in the brainstem, spinal cord, and dorsal root ganglia, regions involved in pain modulation
If you want more context on related symptoms, why did I bruise after my semaglutide injection
Understanding medication side effects is key to safe treatment
The HPA axis is involved in many psychopathological processes, such as depression, and long-term amphetamine abuse can damage the HPA axis, leading to impaired negative feedback, adrenal enlargement, and hypercortisolemia 39,40
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