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It can be done without a whole lot of skill, said Phil Dawson, PhD, a professor of chemistry at Scripps Research in La Jolla, California, who is a former president of the American Peptide Society and board chair of the Peptide Therapeutics Foundation

It is a huge hurdle we and others in the B12 community are working on to overcome

the active site sequence motif and the residues immediately before the cis -Pro and before the serine involved in GSH binding

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