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This reparative effect is mediated, at least in part, through the upregulation and reorganization of key regulatory proteins, most notably protein kinase C (PKC) and the tight junction scaffolding protein zonula occludens-2 (ZO-2), thereby facilitating the reassembly and functional recovery of the tight junction complex (161)
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Key Findings: Lower Oxidative Stress Markers in Aging Rats TBARS Decreased in Liver and Testes The most directly relevant outcome for assessing the glutathione antioxidant intervention was the measurement of TBARS thiobarbituric acid-reactive substances as a marker of lipid peroxidation (LPO)
Front Neurol 12:656349 Choi G, Kim S, Noeske R et al (2025) Evaluation of Glutathione T in the Human Brain Using J-Difference MRS at 3T: Multicenter Multivendor Study
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