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The U.K.s National Institute for Health and Care Excellence, which creates guidance for the National Health Service, recommends two-year limits on the use of some weight loss medications, such as Wegovy

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The hormonal changes from weight loss can affect menstrual cycles, PCOS symptoms, and thyroid function simultaneously, creating a complex picture that requires experienced medical oversight

Similarly, alcohol and over-the-counter pain relievers like acetaminophen are heavily metabolized by the liver and rapidly deplete the body's natural glutathione stores