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In a Phase 2 trial, weight loss with the CagriSema combination reached approximately 15.6%, compared with cagrilintide monotherapy at ~8.1% and semaglutide monotherapy at ~5.1%
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Ipamorelin a selective ghrelin receptor agonist emerged from studies in the 1990s investigating ghrelin mimetics and their ability to stimulate growth hormone release with minimal off-target hormonal effects
HC: Writing original draft
Pedre et al., 2021)
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