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doi: 10.1007/s00384-014-2030-8 106 ZablockaBGoldspinkPHGoldspinkGGoreckiDC

Procedure Preheat spectrophotometer/microplate reader for 30 minutes, adjust the wavelength to 412 nm, set the counter to zero with distilled Preheat Reagent II in water bath for 30 minutes: 37 (mammal cell) or 25 (other species)

Hold in the mouth for 30 seconds before swallowing

411429, 2014 [9] I

J Toxicol Clin Toxicol 2004

A pivotal RCT in 116 cannabis-dependent adolescents found that NAC (1,200 mg twice daily) more than doubled the odds of a negative urine cannabinoid test compared to placebo (OR 2.4, 95% CI 1.1-5.2) (Gray et al., Am J Psychiatry, 2012) [76]