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Notably, despite being a large polyphenol, curcumin is lipophilic and can cross the bloodbrain barrier at sufficient concentrations to exert effects in the CNS (79)

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doi: 10.22038/ijbms.2019.31922.7674 117 KimBHLeeESChoiRNawabootJLeeMYLeeEYet al

Acknowledgments We would like to thank the members of AKs lab for providing intellectual insights into the manuscript