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During perimenopause, estrogen levels fluctuate dramatically before eventually declining, potentially creating periods of increased vulnerability to inflammatory conditions like costochondritis

Blundell, J., Finlayson, G., Axelsen, M., Flint, A., Gibbons, C., Kvist, T., & Hjerpsted, J

and (2) assessing the response to a 50 ms pre-pulse (16 kHz pure tone, 70 dB SPL) in a quiet environment, also presented 100 ms before the startle pulse (110 dB SPL, 50 ms duration), which reflects pre-pulse inhibition (PPI) of the acoustic startle (Fig

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en esos casos puede ser necesario ajustar la dosis

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