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Lower risk of fainting

For sensitive research material, that patience is the whole point

Appropriate candidates for this treatment include people with classic TN pain in whom medications are ineffective or not tolerated, individuals with atypical features or with a diagnosis of trigeminal neuropathy, and individuals who are not deemed to be surgical candidates after review with the neurosurgical team

Human timing is unknown

A 500mcg daily protocol under split dosing would look like: 300mcg upon waking (fasted), then 200mcg approximately 30 minutes before dinner or before bed on an empty stomach