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Studies also indicate that zinc supplementation in type 2 diabetes mellitus patients can reduce fasting blood glucose, HbA1c, and lipid profiles, including TC and LDL-C, while increasing HDL-C, highlighting its potential as a beneficial adjunct therapy for older adults with diabetes [455, 594, 595]

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Moreover, SHED downregulated ECM resolution-associated mediators, such as MMP-2, MMP-9, TIMP-1, and TIMP-2 in the damaged liver [42]

These were dose-dependent and typically transient

Upon binding cytoplasmic DNA, it recruits RIP2 via its WD40 domain, activating NF-B-mediated inflammation

doi:10.1093/ajcn/nqaa015 [53] Gatarek P, Kaluzna-Czaplinska J