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Clayton PT, Whitfield P, Iyer K
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Moreover, a recent study from Guzman and colleagues (39) has shown that, in patients with T2D, treatment with a selective GCGR antagonist, LY2409021, induces a significant increase in hepatic lipid content assessed by magnetic resonance imaging, suggesting that GCGR activation is required to prevent build-up of fat in the hepatocytes
These processes exploit the principle of solubility differences between the desired compound and impurities
The vestibular system and the brainstem nausea centers share overlapping neural pathways
292 In skeletal muscle, CARM1 sustains autophagy and mitophagy during fasting through AMPKULK1 and FOXO3 signaling, thereby preserving muscle integrity
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