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These symptoms are typically mild to moderate and tend to diminish over time, particularly with gradual dose escalation
If youre eating less than usual on a GLP-1, youll need to plan ahead to meet that target
Semaglutide (Wegovy) was approved in 2021 and tirzepatide (Zepbound) in 2023
But the draw of weight loss can be very powerful
What makes Mounjaro different from semaglutide-based products is that it activates two hormone receptors at once: the GLP-1 receptor (which Ozempic and Wegovy target) and the GIP receptor (which plays a role in how the body processes fat and regulates insulin response)
A 2024 systematic review and meta-analysis examining GLP-1 receptor agonists found statistically significant antidepressant effects across multiple studies
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