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Promising safety profile: Early trials report tolerability comparable to incretin-based agents, though higher doses are associated with GI side effects (nausea, diarrhea, vomiting, constipation) Clinical Advantage over Others (Clinical Trial Evidence) Phase 2 obesity studies: At 48 weeks, retatrutide delivered weight reductions up to 24%, far exceeding results reported for monotherapy GLP-1 agents
The discomfort typically presents as mild cramping or a sensation of fullness in the upper abdomen
Here are their benefits: Convenient Oral supplements can be taken at home without a clinic visit
Clinical evidence suggests that adding GLP-1/GIP/glucagon receptor agonists after surgical weight loss may help address weight regain, which affects 20-30% of bariatric patients within 5 years
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These typically subside as your body gets used to the medication dosage
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