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Ethic approval statement The animal use protocol for this study has been reviewed and approved by the Animal Ethics Committee of Hebei General Hospital
The most common side effects include nausea, diarrhea, vomiting, constipation, and abdominal discomfort, which are typically mild to moderate in severity and tend to diminish over time
In addition, we observed that the protein expression of PI3K and p-Akt in the TNC gradually increased in the CM model, and inhibiting the PI3K/Akt pathway by repeated administration of the selective antagonist LY294002 relieved NTG-induced basal tactile allodynia
Supporting electrolyte balance may reduce dryness, fatigue-related dullness, and fluctuations in skin appearance
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