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[20] Pernicious anemia may be present without a person experiencing symptoms at first, over time, feeling tired and weak, lightheadedness, dizziness, headaches, rapid or irregular heartbeat, breathlessness, glossitis (a sore red tongue), poor ability to exercise, low blood pressure, cold hands and feet, pale or yellow skin, easy bruising and bleeding, low-grade fevers, tremor, cold sensitivity, chest pain, upset stomach, nausea, loss of appetite, heartburn, weight loss, diarrhea, constipation, severe joint pain, feeling abnormal sensations including tingling or numbness to the fingers and toes ( pins and needles ), and tinnitus, may occur

Your doctor will determine the appropriate dosage and frequency of the injections based on your individual condition and response to treatment

Vitamin B6B6 is a hard-working vitamin that affects everything from your mood to appetite to skin condition

A condition called pernicious anemia, for example, can lead to severe malabsorption of the nutrient

Common signs that suggest B12 supplementation may be necessary include: Numbness or tingling in hands and feet , which signals peripheral nerve involvement