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Weight-associated health problem: Several health problems stem from carrying excess body weight, including but not limited to type 2 diabetes, cardiovascular disease, hypertension, and sleep apnea
According to Novo Nordisk and independent reporting, the approval was based on strong clinical trial results demonstrating meaningful weight loss outcomes
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To facilitate inter-mice statistics, each rs-fMRI image was spatially smoothed (0.5 mm isotropic Gaussian kernel), and each voxels time series was bandpass filtered from 0.01 to 0.3 Hz [40, 41]