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GLP-1RAs as a support for MCAS For some basics: glucagon-like peptide-1 receptor agonists (abbreviated as GLP-1 medications or as I noted above, GLP-1RAs) are a class of medications that includes semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound, which also work on GIP receptors), as well as in-trials Retatrutide (a triple agonist that works on GLP-1, GIP, and Glucagon receptors)

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Epub 2021 Nov 16

Personalized GLP-1 Responses: Why Genetic Testing Matters The PlexusDx Precision Peptide Genetic Test analyzes GIPR (rs1800437), FTO (rs9939609), and MC4R (rs17782313) variants that relate to GLP-1 and related signaling pathways