Storage protocols describe refrigeration at 2-8C
While direct evidence in humans is limited (for obvious ethical reasons), the mechanism of action is concerning enough to make this one of the most serious GHK-Cu contraindications
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Taken through injection or IV infusion therapy, glutathione directly enters the bloodstream without any degradation of the bonds holding the tripeptide together
This phenomenon has been corroborated by autopsy findings in PD patients, which reveal a significant presence of activated microglia in the substantia nigra and basal ganglia regions of their brains, whereas microglia in the brain tissue of healthy individuals remain in a quiescent state (He et al., 2018)