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Figure 1: A medieval urine wheel from Epiphanie Medicorum, a medical textbook printed in Nuremberg, Germany in c.1506 by Ullrich Pinder

MT-1 shows high selectivity for MC1R receptors with minimal MC3R/MC4R cross-reactivity, meaning it produces melanogenesis without the appetite suppression or sexual side effects characteristic of melanotan-2

These effects are generally mild and tend to diminish over time

Neurochem 116 , 164176 (2011)

It has antiandrogen effects that matter for some hair conditions

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