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Semaglutide and cancer: a systematic review and meta-analysis
Glucagon-like peptide-1 receptor agonists and the risk of obesity-related cancers: a systematic review and meta-analysis
While not a complete list of warnings and adverse reactions, the most common side effects of GLP-1 drugs generally include: Nausea and/or vomiting, which most often occur after starting the medication and typically ease with time Diarrhea Abdominal discomfort, which may be accompanied by bloating or cramping
The cases of suicide or self-injury reported to FAERS do not indicate any overall safety signal attributable to GLP-1RA at this time
They are often related to dehydration, reduced caloric intake, or caffeine withdrawal if coffee consumption decreases alongside overall food intake
SLC25A39 as well as mitochondrial GSH may also represent promising drug targets for cancer, since manipulating SLC25A39 functioning or mitochondrial GSH in tumor cells may induce selective oxidative stress, leading to cell death
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