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In a clinical trial, participants with obesity (without diabetes) experienced an average weight loss of 20% with tirzepatide, compared to 13.7% with semaglutide after 72 weeks
When adverse effects do occur, they are usually mild and transient, often related to the route of administration rather than the vitamin itself
however, clinical trials in humans are very limited
This means it stimulates GLP-1 receptors to reduce appetite and enhance insulin secretion, while blocking GIP signaling, which may help prevent fat storage
Lab testing is not always necessary, but it may be recommended if symptoms persist or there is concern about a deficiency
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