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[1] [2] It belongs to a class of medicines called glucagon-like peptide-1 (GLP-1) receptor agonists , which were originally developed for type 2 diabetes management but have demonstrated significant efficacy in weight reduction

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0.1% (placebo) Steady State: Achieved after 4-5 weeks of weekly dosing Safety: Nausea (68% at 4.5 mg), vomiting (32%), generally mild-moderate and transient Discontinuation: 14% discontinued due to GI adverse events Appetite Effects: Significant reductions in Visual Analogue Scale (VAS) hunger scores Publication: Lau DCW, et al

Previous research had shown that infusing GLP-1 into people continuously over time significantly reduced appetite and led to weight loss, but there was no practical way to achieve this with a supplement

Seminal early studies offering critical mechanistic insights were also included, and additional relevant articles were identified through reference mining