doi:10.1097/MD.0000000000038236 49
The article says semaglutide is approved in Canada as Ozempic for diabetes and Wegovy for weight management, and tirzepatide as Mounjaro for diabetes
These drugs have come to market in a period of widespread adoption of virtual care
This can lower beneficial compounds like short-chain fatty acids (SCFAs), which influence everything from weight to mood and immunity, and make constipation worse if fibre and fluids arent kept up, explains BDAs Ludlam-Raine
The efficacy and safety profiles of short-, long-, and prolonged-acting GLP-1 analogs (exenatide, liraglutide, or exenatide LAR, respectively) were recently evaluated in a meta-analysis including 25 randomized controlled trials
the compound's evidence base is limited to preclinical in vitro and animal (largely rodent) studies of IGF-1 receptor activation, muscle-cell signaling, and tissue repair, with human safety and efficacy data for this specific analog effectively absent