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Yet both of these experimental approaches can be informative to evaluate how formulation composition modulates PPIs, and thereby, viscosity, and aggregation

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Valdivia A, Ly J, Gonzalez L, Hussain P, Aing T, Islamoglu H, et al

Levels of Glp1r mRNA were not different in the kidney or renal artery of Glp1r Tie2+/+ versus Glp1r Tie2/ mice but were markedly reduced in the lung of Glp1r Tie2/ mice, a tissue enriched in ECs (Figure 3, DF)

Conversely, a portion of uric acid is secreted back into the proximal tubular lumen through various apical transporters, including ABCG2, NPT1, NPT4, and GLUT9, along with the basolateral transporters OAT1 and OAT3