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Semaglutide 2.4 mg (Wegovy) produced an average 15 % weight reduction at 68 weeks in the STEP-1 trial.[pmc.ncbi.nlm.nih.gov] Tirzepatide 15 mg (Zepbound) delivered up to 22 % weight loss at 72 weekscurrently the largest seen with an approved injectable

The current wave is the largest in pharma history by pre-LOE revenue at risk

Dehner C, Moon CI, Zhang X, Zhou Z, Miller C, Xu H, et al

[54] Medical uses [edit] Replacement therapy [edit] GH is used as replacement therapy in adults with GH deficiency of either childhood-onset or adult-onset (usually as a result of an acquired pituitary tumor)

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