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Treatment with survodutide also showed meaningful metabolic improvements, including reductions in waist circumference, a key predictor of cardiometabolic risk

A study assessing the acute effect of liraglutide in vagotomized subjects did implicate the vagus nerve in mediating the appetite effect (188), but the sample size in the study was small and subjects had a very low appetite at baseline, making it difficult to draw conclusions

Kidney or liver problems : Severe kidney or liver impairment may affect how these medications are processed in your body