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BACE1 physiological functions may limit its use as therapeutic target for alzheimers disease
Shoba, G., Joy, D., Majeed, M., et.a
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Considering the broader genetic background, pharmacogenomic variability may further contribute to treatment heterogeneity, as genetic variants affecting GLP-1 receptor signaling, appetite regulation, insulin secretion, and hostmicrobiota interactions could influence individual responsiveness (126)
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