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Hence, more studies with human subjects are still required to reach a conclusive decision

The use of Drosophila bring to the study of oxidative liver injury many advantages, including ease of genetic manipulation, availability of genetic mutants and constructs, ease of germ-free generation, relatively short lifespan, amenability to high-throughput screening, and overall cost relative to murine models 40

And then again, tolerability

Mycotoxins (e.g., ochratoxin A, gliotoxin), heavy metals (e.g., mercury, aluminum), and volatile organic compounds can all provoke mast cell degranulation and immune dysregulation

Gene Regulation: Downregulates senescence markers like p16 (INK4a) and p21 (Waf1), delaying cellular aging

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