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10.1016/j.regpep.2012.12.007 7 BecejacT.CesarecV.DrmicD.HirslD.MadzaracG.DjakovicZ.et al (2018)

Consistent with this, hepatocyte-specific overexpression of DPP4 in mice results in increased hepatic steatosis, liver enzymes, and markers of inflammation (25)

Spice Wisely: If spicy foods trigger nausea, experiment with milder spices or reduce the amount you use

Patients should seek medical advice if headaches are accompanied by: Neurological symptoms : Vision changes, weakness, numbness, difficulty speaking, confusion, or loss of consciousness Severe nausea and vomiting : Particularly if unable to maintain adequate hydration or take medications for more than 24 hours Signs of dehydration : Markedly decreased urination, dark urine, dizziness, rapid heartbeat, or dry mucous membranes Fever or neck stiffness : Which may suggest infection requiring evaluation Changes in headache pattern : New characteristics in patients with pre-existing headache disorders New onset after age 50 : Headaches beginning later in life require evaluation Severe, persistent abdominal pain with or without vomiting : May indicate pancreatitis, a rare but serious side effect of GLP-1 medications requiring immediate medical attention Healthcare providers may recommend several approaches when evaluating persistent headaches

This process ensures that it wont break down before your body has a chance to absorb it

The FDA labeling includes significant warnings and contraindications that apply to all patients, including those with IBS