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This ongoing oxidative stress leaves endothelial cells (the lining of blood vessels) highly vulnerable to ongoing damage, contributing to the micro-clotting and "immunothrombosis" frequently observed in Long Haulers

The article says DPP-4 inhibitors carry a small risk of joint pain and rare reports of severe infections, and it flags severe renal impairment, citing an eGFR below 15 for some DPP-4 agents, as a caution

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