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Brain section slides were stained with Congo red to evaluate amyloid plaques by averaging the number of plaques in ten different fields under 10x magnification in multiple areas of the brain blindly by two separate observers

Each freeze-thaw cycle degrades approximately 5-8% of peptide via ice crystal shearing and pH fluctuation during phase transitions

Hyperglycemic conditions prime cells for RIP1-dependent necroptosis

These cells secrete pro-inflammatory cytokines, chemokines, and ROS, amplifying inflammation and activating ferroptosis

669 Clinical trials have demonstrated that DFO can facilitate the absorption of edema and hematoma after TBI, reduce neuronal degeneration and phospholipid injury