Interestingly, the neural circuits responsible for the metabolic effects of GLP-1R agonism may be distinct from those mediating nausea or malaise (Huang et al., 2024), suggesting that future therapies could be tailored to preserve metabolic benefits while minimizing gastrointestinal side effects
It's considered a cause of inflammation and a risk factor for high blood pressure, stroke, and heart disease
the study period for this analysis started in 2013 when SGLT2 inhibitors became available
Whether youre new to GLP-1 medications or looking for ways to optimize your results, pairing these treatments with expert medical supervision and a nutritious diet is key
This is also the dose level where the conversation about whether to continue escalating or hold at the current dose becomes medically relevant
Another theory is that GLP-1s (glucagon-like peptide-1 receptor agonists) the class of medication semaglutide belongs to can cause nausea