Among patients who originally took Mounjaro, those on placebo regained just over 50% of the lost weight at week 52
Given this complex picture, although mitochondrial dysfunction, suggested by a number of studies [60], is a plausible reason for lactate elevations in ME/CFS, the other possibilities should not be discarded
However, the digestive system also contains an enzyme that breaks down GLP-1
The two compounds operate through largely separate biological pathwaysGLP-1 receptors versus AMPK activationwhich is why researchers have theorized potential synergistic benefit
Its important to note that periodic lab tests may be required to monitor your bodys response to the medication and ensure safety
79 (Note that the formula for VSL#3 changed in 2016 and the original, studied formula is now available in a commercial product called Visbiome)