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Vomiting is a higher risk symptom because it drives dehydration
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People with insulin resistance, thyroid conditions, or other hormonal factors may see a modified response curve compared to the trial averages
OShea K, Nash R
Turner LV et al
Additionally, many human diseases characterized by demyelination (e.g., MS and neuromyelitis optica) show early disruption of gap junctions between astrocytes and oligodendrocytes and a decline in connexin proteins (Markoullis et al., 2012
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