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The initial twice-daily formulation was discontinued due to exceptionally high rates of gastrointestinal adverse events (nausea and vomiting), leading to discontinuation rates exceeding 50% in trials

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& Snehalatha, C

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doi: 10.1172/jci.insight.141299 124 YaoXZhangYHaoJDuanHQZhaoCXSunCet al

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