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(ii) glutamine-derived aspartate supports eukaryotic translation initiation factor 5 A (EIF5a) hypusination and HIF1 translation, promoting metabolic changes, i.e., enhanced glycolysis, in tumor-associated macrophages, which is correlated to advanced tumors [180]
Chang, R., Ng, T
Calibration may therefore be biologically coherent, while the strength of the evidence remains dose-dependent
de Jong M, van der Worp HB, van der Graaf Y, Visseren FLJ, Westerink J
J Clin Endocrinol Metab (2020) 105(8):e27106
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