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Anti-diabetic effects Accounting for 9095% of diabetic population, type 2 diabetes mellitus (T2DM) has increased rapidly in recent decades worldwide, and the morbidity and mortality associated with secondary complications of the disease, such as retinopathy, nephropathy, and cardiovascular disease, also have increased significantly.Citation 51 ) T2DM is characterized by mitochondrial disorder and chronic hyperglycemia and dyslipidemia resulting from insulin resistance of the peripheral tissues and impaired insulin secretion from the pancreas.Citation 52 ) Mitochondria regulate metabolic pathways through signal transduction that is essential for metabolic homeostasis and cellular function
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Steroid modulation of the GABAA receptor complex: electrophysiological studies