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-thalassaemia major results in ineffective haemoglobin synthesis that requires chronic red blood cell transfusions, which might result in iatrogenic iron accumulation, hypogonadism and/or aberrant spermatogenesis
It is available by prescription only and should be administered by a healthcare professional
When used alone, the inhibition of 5-LOX by Zileuton led to the accumulation of AA
(download XLSX Statistical source data for Figs
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