Sjstrm L, Rissanen A, Andersen T, Boldrin M, Golay A, Koppeschaar HP, et al
A research presentation titled "Much Ado About Nothing: Tirzepatide and Medullary Thyroid Cancer Debunked," presented at the Endocrine Society annual meeting, directly addressed the disconnect between the boxed warning and clinical evidence, arguing that the accumulating data strongly suggest the warning will eventually be revised as human evidence continues to show no signal
Although there is currently no link established between susceptibility to infections and immune dysregulation in these patients, the laboratory results were not available for most of the patients
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Retinal pigment epithelial cells have been reported to express functional GLP-1 receptors, and preclinical literature has explored retinal neuroprotection and anti-inflammatory effects
The 19 states that cover obesity indications did so through explicit legislative mandates or budget appropriations