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Regulatory decisions are anticipated in 2026

3.3 Proposed Mechanism for the Difference in the Semaglutide Pharmacokinetic Profile Observed Between IcoSema and Semaglutide Administration The change in the semaglutide pharmacokinetic profile when semaglutide is combined with icodec in IcoSema gave rise to the hypothesis that there could be an interaction between icodec and semaglutide locally at the injection site in the subcutaneous tissue, since both molecules bind to albumin

Common concentrations include 10 mg/mL, 15 mg/mL, and 20 mg/mL

Baseline body weight and composition significantly affect outcomespatients with higher initial BMI may experience greater absolute weight loss but similar percentage reductions compared to those with lower baseline weights