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It is also a precursor of glutathione, an intracellular antioxidant that protects cells from oxidative damage
On the other hand, glutathione, a still relatively under-the-radar antioxidant, does occur naturally in the body
To assess whether RT probe binds to any proteins or reacts with free cysteine residues in some proteins that may interfere with the final ratio readouts, we incubated RT with cell lysate, which was dialyzed using a 3 K cut-off membrane to remove all small molecules including GSH, and observed no significant changes in fluorescent signal ratios even at the highest lysate concentration shown (protein concentration is 36 mg ml 1 based on a BCA assay), suggesting that there is no non-specific interactions or reactions between cellular proteins and RT which could significantly change the ratio readouts (Fig
BPC-157 is investigated in preclinical research for its effects on tissue regeneration, angiogenesis, fibroblast migration, and cellular signaling across tendon, ligament, muscle, gastrointestinal, and vascular models
Washington (DC): National Academies Press
Toxicology and Industrial Health, 32, 160718
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