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PDE5 inhibitor: sildenafil Sildenafil has demonstrated therapeutic efficacy in HAPH patients

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It is worth noting that while the aforementioned studies have validated the efficacy of nanomaterials in inhibiting NLRP3 inflammasome-mediated pyroptosis, systematic comparisons of their specific intervention targets at different stages remain lacking

Therefore, the ratio between reduced and oxidized forms of GSH is an important indicator of the redox environment and, at the same time, contributes to the accomplishment of the molecular mechanisms underlying cell proliferation, differentiation or death in the form of apoptosis (Dickinson and Forman, 2002)