One question researchers are exploring is whether prolonged use of GLP-1 receptor agonists could affect the bodys own hormone production after the medication is stopped
Steady decline in ATP production was observed in MG-treated INS-1 and MIN6 cells
Glp-1 analog, liraglutide, ameliorates hepatic steatosis and cardiac hypertrophy in C57BL/6J mice fed a Western diet
However, over the next year, initiation slowed and even reversed: with first-time prescribing rates declining 31% by June 2025, reflecting an average month-over-month decrease of 0.004 percentage points
Other side effects included, but are not limited to, minor (NNTH 36, RR: 2.17, 95%CI: 1.38 to 3.43, p = 0.03), symptomatic (NNTH 22, RR: 1.78, 95%CI: 1.15 to 2.74, p = 0.03) hypoglycemic events, dizziness (NNTH 60, RR: 1.39, 95%CI: 1.03 to 1.87, p = 0.04) (Table 5)
As September progressed, my weight was 115 lbs, and I wanted to start tapering