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This mechanism is why SGLT-2 inhibitors carry FDA warnings about increased UTI and genital infection risk

GLP-1 agonists act by mimicking the GLP-1 hormones effects, stimulating insulin secretion when you eat and helping regulate blood sugar levels

Editorial note: No randomized controlled trial has yet tested resistance training as a counter-measure specifically to GLP-1-induced lean-mass loss

2020 (JCI Insight) Mechanistic follow-up: tesamorelin shifted liver transcriptomic signatures toward oxidative phosphorylation and reduced inflammatory signaling

announced the decision to discontinue the development of Danuglipron (PF-06882961), an oral GLP-1 receptor agonist previously investigated for chronic weight management

Wegovy Wegovy is marketed as a weight loss drug for chronic weight management for adults to treat obesity