Other GLP-1 and glucagon co-agonists in early phase clinical trials as treatments for obesity include AZD9550 and LY3305677 (NCT05623839)
Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial
BPC 157 may be beneficial for those dealing with gut health conditions like leaky gut syndrome, ulcerative colitis, or irritable bowel syndrome
Appetite and food reward 3-arm Phase 1 tirzepatide vs liraglutide 3.0 mg vs placebo: measured lunch intake fell 524.6 kcal vs placebo by week 3 (about 72% of that difference remained at week 6), with craving and hedonic-hunger reductions exceeding liraglutide
BPC-157 exhibits minimal side effects, moderate oral and excellent subcutaneous bioavailability in mice
You may consider utilizing standalone adaptogens such as holy basil (tulsi), shatavari (available via Fullscript you can sign up with my credentials here ), reishi , or rhodiola (available via Fullscript you can sign up with my credentials here ), starting with one herb at a time