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GLP-1 receptor agonists and the dual GIP/GLP-1 receptor agonist tirzepatide represent major therapeutic advances, offering improved glycemic control, cardiovascular benefits, and significant weight reduction for appropriate patients
An adjusted indirect treatment comparison found that tirzepatide 10 mg and 15 mg produced significantly more weight loss than semaglutide 2 mg, with differences of approximately 3.15 kg to 5.15 kg
Onakpoya, I., Hung, S
Am J Ophthalmol 1995 Jun
Retatrutide (12mg): Up to 28.7% body weight reduction over 68 weeks in TRIUMPH-4
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