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Although prolonged GSH depletion induced triglyceride depletion and reduced epididymal adipose tissue in mice, it induced a sex-dependent requirement of NRF2 expression in the liver

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In addition it enables the body to rid itself of unwanted toxins and heavy metals, detoxifying the liver, the bodys most concentrated source of glutathione

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Oncogene (2004) 23:244253.10.1038/sj.onc.1207358 17 FujiiJIuchiYOkadaF