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The upregulation of interferon-stimulated gene 15 in TECs disrupted mitochondrial homeostasis and triggered the release of mtDNA into the cytosol, which then triggers NLRP3mediated pyroptosis in cyclic GMP-AMP synthase-stimulator of interferon genes pathway (47)

When GABA is bound to its receptor, it causes sedative effects

We also tested another gene spxB that encodes a pyruvate oxidase catalyzing pyruvate, phosphate and O 2 to acetyl phosphate, CO 2 and H 2 O 2 (Lisher et al., 2017)

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Drug Resist Update