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Int J Oncol (2018) 52(5):166173
Frequently Asked Questions Is glutathione safe for long-term use
The exogenous induction of GSH depletion causes mitochondrial-dependent apoptosis in CYP2E1-expressing HepG2 cells (E47 cells) [123]
Vitamin C stimulates the activity of glutathione to recycle oxidised glutathione and also to enhance antioxidant recycling
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This distinction is critical: absence of documented harm in a poorly studied compound is not the same as demonstrated safety
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