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Hydration and blood volume status Monitor hydration status, especially in elderly patients or those with renal impairment, as SGLT2 inhibitors increase urinary excretion and may lead to dehydration or hypotension
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Moreover, the drug reduced the risk of cardiac-related death in patients with obesity and cardiovascular disease by 15%, and the risk of developing diabetes all the patients in the trial were diabetes-free by 73%
This is a normal physiological response
Magnesium Supplements : Magnesium citrate or magnesium oxide can help relieve constipation, but use with caution as they may interact with certain medications